Micelle Mixtures for Coadministration of Gemcitabine and GDC-0449 to Treat Pancreatic Cancer
Investigators report the use of methoxy poly(ethylene glycol)-block-poly(2-methyl-2-carboxyl-propylene carbonate)-graft-dodecanol copolymer for conjugating gemcitabine and encapsulating a Hedgehog inhibitor, vismodegib, into its hydrophobic core for treating pancreatic ductal adenocarcinoma. [Mol Pharm] Abstract
Replicative Capacity of β-Cells and Type 1 Diabetes
The reviewers highlight features of the β-cell, including it being part of a pancreatic islet, a mini-organ that is highly vascularized and highly innervated, and efforts to promote β-cell proliferation. [J Autoimmun] Abstract
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Echo Therapeutics Announces Significant Progress in Key Development Milestones
Echo Therapeutics, Inc. announced important advances in its next generation continuous glucose monitoring system and its progress toward commercialization in China. Important advancements were made in the NextGen sensor element, hydrogel and other key components of the company’s highly disruptive technology to the episodic, needle-based glucose monitoring business. [Echo Therapeutics] Press Release
Government of Canada Combats Chronic Health Conditions
The Honourable Jane Philpott, Minister of Health, announced an investment of $16 million over five years to support new research that will help find new ways to prevent or treat chronic conditions affecting millions of Canadians. [Government of Canada] Editorial